Thromboembolic diseases are increasing worldwide and always require anticoagulant therapy.We still need safer and more secure antithrombotic drugs than those presently available.Sulfated polysaccharides from marine organisms may constitute a new source for the development of such drugs.Investigation of these compounds usually attempts to reproduce
Abstract Background Stroke is a significant contributor of worldwide disability and morbidity with substantial economic consequences.Rehabilitation is a vital component of stroke recovery, but inpatient stroke rehabilitation programs can struggle to meet the recommended hours of therapy per day outlined by the Canadian Stroke Best Practices and Ame
Abstract We show how to combine higgsed topological vertices introduced in [7] with conventional refined topological vertices.We demonstrate that the extended formalism describes very general interacting D5-NS5-D3 brane systems.In particular, we introduce new Platters types of intertwining operators of Ding-Iohara-Miki algebra between different typ
The liver is a vital organ involving in various major metabolic functions in human body.MicroRNA-122 (miR-122) plays an important role in the regulation of liver metabolism, but its intrinsic physiological functions require further clarification.This study integrated the genome-scale metabolic model of hepatocytes and mouse experimental data with g
Introduction: Osteoporosis remains an undertreated disease entity causing substantial morbidity and mortality.Proximal humerus fractures are a common sentinel fracture, providing an opportunity to intervene with antiresorptive therapy before more subsequent fractures occur.Despite the success of Folic Acid/ Vitamin B-9 programs aimed to improve pos